TF-IDF – Guideline Analytics

Term Frequency-Inverse Document Frequency - Next step is to apply this to recs categorized by Action Type and then use to predict Action Type
term	concepts	term_frequency	idf	TF-IDF
wound	[wound, may, wr, approximat, oth, be]	0.16666666666666666	4.430816798843313	0.7384694664738856
serologic	[are, prefer, method, diagnos, wr, serologic, test, tularemia]	0.125	5.817111159963204	0.7271388949954005
microbiology	[is, laboratory, sr, notify, suspect, microbiology, tularemia, if]	0.125	4.430816798843313	0.5538520998554142
retention	[diuretic, retention, hfref, recommend, patient, fluid, are]	0.14285714285714285	3.7376696182833684	0.5339528026119097
bacterial	[organism, antibiotic, table, begin, treatment, antibiotic, bacterial, currently, patient, resistant]	0.2	2.5982353350950036	0.5196470670190008
hfref	[all, ace, are, hfref, recommend, inhibitor, patient]	0.14285714285714285	3.619886582626985	0.5171266546609978
correct	[deficiencie, correct, hfref, therapie, than, recommend, oth, are, hormonal, not]	0.1	5.123963979403259	0.5123963979403259
hap	[recommend, day, patient, we, hap, therapy, course, antimicrobial]	0.125	4.02535169073515	0.5031689613418937
bioterrorism	[bioterrorism, or, recommend, po, levofloxacin, q24h, cas, presum, mg, po, ciprofloxacin, aerosol, mg, day, because, exposure, is, iv, bid]	0.10526315789473684	4.718498871295094	0.49668409171527306
refractory	[congestion, ultrafiltration, therapy, refractory, patient, respond, consider, not, may, be, medical]	0.09090909090909091	5.123963979403259	0.46581490721847807
csf	[stimulat, therapy, csf, adjunct, transfusion, or, gm, colony, granulocyte, factor, csf]	0.09090909090909091	5.123963979403259	0.46581490721847807
persistent	[neutropenia, initial, their, persistent, presentation, unexplain, subsequent, episode, fev, neutropenia, current, fev, is, determine, recurrent, aft, day, patient, from, or, neutropenia, wheth, episode, fev, initial, or, episode, fev]	0.10714285714285714	4.207673247529104	0.4508221336638325
therapy	[reasonable, are, inhibitor, arb, therapy, line, alternatif, as, ace, first, as, hfref]	0.08333333333333333	5.123963979403259	0.4269969982836049
restriction	[fluid, is, hyponatremia, reasonable, stage, symptom, congestive, patient, restriction, especially, reduce]	0.09090909090909091	4.430816798843313	0.40280152716757395
block	[block, iii, tolerat, dose, clas, nsr, rate, nyha, bpm, maximally, beta, heart, ii]	0.07692307692307693	5.123963979403259	0.39415107533871224
weight	[ultrafiltration, patient, consider, alleviate, symptom, may, be, weight, volume, obviou, overload, fluid, congestive]	0.07692307692307693	5.123963979403259	0.39415107533871224
consider	[might, hospitalization, hfpef, decrease, use, arb, be, consider, patient]	0.1111111111111111	3.5145260669691587	0.3905028963299065
channel	[recommend, not, hfref, as, are, calcium, treatment, channel, drug, bloc, routine]	0.09090909090909091	4.207673247529104	0.38251574977537306
stable	[beta, recommend, blocker, use, reduce, is, proven, all, mortality, stable, patient]	0.09090909090909091	4.207673247529104	0.38251574977537306
improve	[improve, advanc, life, quality, palliative, care, supportive, hf, effective, is, symptomatic, patient]	0.08333333333333333	4.430816798843313	0.3692347332369428
harm	[ventilation, central, sleep, adaptive, apnea, nyha, clas, hfref, servo, iv, harm, ii, patient, caus]	0.07142857142857142	5.123963979403259	0.36599742710023275
hemodynamic	[mental, instability, do, hemodynamic, alter, outpatient, recommend, who, therapy, sir, is, statu, have, not, patient, or]	0.0625	5.817111159963204	0.36356944749770026
intolerant	[ace, intolerant, are, hfref, recommend, are, inhibitor, patient, arb, who]	0.1	3.619886582626985	0.36198865826269855
use	[is, patient, nutritional, recommend, hfpef, not, use, supplement, routine]	0.1111111111111111	3.2521618025016674	0.3613513113890741
assessment	[assessment, situation, patient, hf, reasonable, plan, viability, when, cad, is, select, revascularization]	0.08333333333333333	4.207673247529104	0.35063943729409197
without	[not, event, recommend, af, patient, chronic, thromboembolic, source, hfref, prior, anticoagulation, is, without, or, cardioembolic]	0.06666666666666667	5.123963979403259	0.34159759862688394
correct	[prior, symptom, or, hormonal, not, deficiencie, patient, are, correct, current, therapie, oth, than, hfref, recommend]	0.06666666666666667	5.123963979403259	0.34159759862688394
good	[indicat, comorbiditie, not, patient, survival, functional, frailty, good, crt, year, capacity, is, limit, or, whose]	0.06666666666666667	5.123963979403259	0.34159759862688394
cpap	[apnea, quality, disease, cardiovascular, improve, be, obstructive, patient, sleep, may, cpap, sleepines, daytime, sleep, reasonable]	0.06666666666666667	5.123963979403259	0.34159759862688394
clinical	[consider, addition, observational, mucormycosi, an, data, echinocandin, murine, model, bas, be, clinical, synergy, could, wr]	0.06666666666666667	5.123963979403259	0.34159759862688394
discontinuation	[use, patient, antibiotic, discontinuation, we, cpi, vap, hap, not, guide, therapy, sug, suspect]	0.07692307692307693	4.430816798843313	0.34083206144948563
beneficial	[as, when, are, prescrib, not, hf, adjunctive, beneficial, solely, statin, therapy]	0.09090909090909091	3.7376696182833684	0.3397881471166699
treatment	[as, patient, nutritional, are, current, supplement, hfref, recommend, hf, prior, symptom, or, treatment, not]	0.07142857142857142	4.718498871295094	0.3370356336639353
therapy	[duration, patient, we, long, therapy, rath, vap, course, antimicrobial, than, recommend, day]	0.08333333333333333	4.02535169073515	0.3354459742279291
hydralazine	[hfref, dinitrate, arb, ace, hydralazine, who, isosorbide, be, useful, can, combination, patient, inhibitor, be, or, can, given]	0.11764705882352941	2.772588722239781	0.3261869084987978
acutely	[peptide, admission, level, cardiac, natriuretic, decompensat, acutely, useful, establish, measurement, biomarker, is, hf, troponin, baseline, prognosi, or, hospital]	0.05555555555555555	5.817111159963204	0.323172842220178
treatment	[q12h, tularemia, iv, im, treatment, gentamicin, or, is, kg, q8h, cas, mg, streptomycin, recommend, kg, severe, sr, mg]	0.05555555555555555	5.817111159963204	0.323172842220178
beneficial	[be, can, decrease, hfref, hospitalization, beneficial, hf, digoxin, contraindicat, patient, unles]	0.09090909090909091	3.5145260669691587	0.319502369724469
beneficial	[be, unles, hospitalization, patient, beneficial, contraindicat, can, hf, decrease, hfref, digoxin]	0.09090909090909091	3.5145260669691587	0.319502369724469
hydral	[black, implment, clas, nyha, nitrate, iii, hydral, patient, iv]	0.1111111111111111	2.872672180796764	0.3191857978663071
revascularization	[be, arteriography, iia, revascularization, ischemia, is, when, coronary, eligible, may, hf, contribut, patient, reasonable]	0.07142857142857142	4.430816798843313	0.31648691420309377
vancomycin	[indicat, linezolid, vancomycin, coverage, empiric, mrsa, we, or, is, if, recommend, eith]	0.08333333333333333	3.7376696182833684	0.3114724681902807
period	[low, score, day, patient, few, anticipat, multinational, neutropenia, period, high, risk, brief, anc, those, are, patient, profound, or, stratify, neutropenia, fev, risk, susceptibility, mascc, comorbiditie, association, those, are, or, cell, accord, day, prolong, patient, care, risk, mascc, anticipat, neutropenia, infection, supportive]	0.07317073170731707	4.207673247529104	0.30787853030700757
mild	[po, recommend, mild, sr, mg, tetracycline, tularemia, treatment, mg, doxycycline, qid, or, bid, is, cas]	0.06666666666666667	4.430816798843313	0.2953877865895542
colistin	[are, adequate, available, activity, patient, sug, suspect, avoid, negative, alternative, colistin, vap, agent, gram, we, if]	0.0625	4.718498871295094	0.2949061794559434
alternative	[activity, aminoglycoside, patient, sug, suspect, avoid, negative, alternative, vap, agent, gram, we, if, are, adequate, available]	0.0625	4.718498871295094	0.2949061794559434
stage	[where, recommendation, patient, stage, clas, list, are, appropriate, as, patient, stage, appropriate, as, c., measure, recommend]	0.0625	4.718498871295094	0.2949061794559434
improve	[able, or, improve, are, regular, as, train, hf, activity, exercise, participate, effective, physical, recommend, patient, who, is, statu, safe, functional]	0.05	5.817111159963204	0.2908555579981602
implement	[nyha, aldosterone, provid, cor, implement, meq, min, antagonist, crcl, iv, est, ii, ml, clas]	0.07142857142857142	4.02535169073515	0.28752512076679637
day	[treat, an, day, against, recurrent, aft, antibiotic, course, culture, isolat, obtain, absces, pathogen, active]	0.07142857142857142	4.02535169073515	0.28752512076679637
without	[hfref, or, no, not, without, af, recommend, event, prior, chronic, patient, cardioembolic, anticoagulation, thromboembolic, source, is, benefit, iii]	0.05555555555555555	5.123963979403259	0.28466466552240327
lbbb	[clas, nsr, lvef, ms, nyha, iv, lbbb, qrs, ii, pattern]	0.1	2.8213788864092133	0.2821378886409213
penicillin	[cefazolin, eg, treatment, penicillin, pyomyositi, mssa, or, nafcillin, is, sr, caus, recommend, antistaphylococcal, or, oxacillin]	0.06666666666666667	4.207673247529104	0.2805115498352736
blood	[thorough, additional, imag, physical, infection, che, radiograph, culture, blood, includ, through, che, extent, ct, examination, determine]	0.0625	4.430816798843313	0.2769260499277071
dyspnea	[measurement, dyspnea, or, is, exclusion, hf, biomarker, present, diagnosi, support, peptide, patient, natriuretic, useful]	0.07142857142857142	3.871201010907891	0.2765143579219922
useful	[postdischarge, hospitalization, predischarge, hf, prognosi, dur, peptide, level, natriuretic, be, useful, establish, can]	0.07692307692307693	3.5145260669691587	0.2703481589976276
information	[pk, vap, dos, that, rath, sug, pd, data, than, hap, prescrib, use, manufactur, be, antibiotic, patient, we, information, determin]	0.05263157894736842	5.123963979403259	0.26968231470543463
suspicion	[gangrene, associat, aggressive, surgical, suspicion, infection, prompt, is, recommend, or, necrotiz, gas, systemic, patient, consultation, or, toxicity, fasciiti, sign]	0.05263157894736842	5.123963979403259	0.26968231470543463
transplantation	[transplantation, gdmt, surgical, evaluation, select, carefully, is, patient, management, indicat, despite, device, hf, stage, cardiac]	0.06666666666666667	4.02535169073515	0.2683567793823433
size	[be, initial, present, thicknes, hf, dimensional, dur, wall, ventricular, evaluation, size, function, asses, valve, echocardiogram, wall, perform, doppl, motion, function, should, patient]	0.045454545454545456	5.817111159963204	0.2644141436346911
blood	[are, injurie, patient, immunodeficiency, immersion, neutropenia, blood, mediat, cell, bite, animal, severe, chemotherapy, malignancy, recommend, culture]	0.0625	4.207673247529104	0.262979577970569
marrow	[or, myonecrosi, necrotiz, surgical, marrow, soft, intervention, fasciiti, recovery, absces, tissue, drainage, recommend, is, aft, or, polymicrobial, progressive]	0.05555555555555555	4.718498871295094	0.2621388261830608
early	[within, day, is, early, telephone, discharge, schedul, visit, an, up, early, follow, hospital, within, day, reasonable, up, follow]	0.05555555555555555	4.718498871295094	0.2621388261830608
routine	[or, increase, phosphodiesterase, patient, hfpef, use, ineffective, inhibitor, routine, activity, or, is, nitrate, qol]	0.07142857142857142	3.619886582626985	0.2585633273304989
resonance	[recommend, pyomyositi, mri, modality, imag, scan, establish, tomography, studie, ct, useful, diagnosi, resonance, ultrasound, imag, magnetic, are, is, comput, also]	0.05	5.123963979403259	0.25619819897016294
quantitative	[noninvasive, than, vap, culture, sug, we, sampl, invasive, rath, semiquantitative, culture, quantitative, sampl, noninvasive, than, rath, culture, diagnose, quantitative, sampl]	0.05	5.123963979403259	0.25619819897016294
mupirocin	[daily, decontamination, decolonization, item, consid, intranasal, wash, regiman, mupirocin, sheet, day, bid, infection, towel, aureu, recurrent, such, daily, as, clothe, personal, chlorhexidine, s.]	0.043478260869565216	5.817111159963204	0.2529178765201393
dicloxacillin	[usually, are, or, ecthyma, impetigo, methicillin, is, staphylococcu, cephalexin, dicloxacillin, aureu, from, isolate, because, susceptible, recommend]	0.0625	4.02535169073515	0.25158448067094685
harmful	[is, ace, harmful, aldosterone, inhibitor, hfref, routine, patient, an, potentially, antagonist, combin, arb, use]	0.07142857142857142	3.5145260669691587	0.2510375762120827
harmful	[combin, routine, is, patient, arb, harmful, inhibitor, aldosterone, ace, hfref, antagonist, an, potentially, use]	0.07142857142857142	3.5145260669691587	0.2510375762120827
omega	[therapy, supplementation, or, as, omega, patient, reasonable, adjunctive, use, pufa, hfpef, hfref, is]	0.07692307692307693	3.2521618025016674	0.2501662925001283
therapy	[therapy, patient, we, not, sug, antibiotic, provid, vat]	0.125	1.988469763474109	0.24855872043426364
hemodynamic	[response, symptomatic, normotensive, monitor, invasive, congestion, hf, recommend, hemodynamic, diuretic, patient, use, vasodilator, acute, is, decompensat, routine, not]	0.05555555555555555	4.430816798843313	0.2461564888246285
penicillin	[therapy, sr, clindamycin, clostridial, definitive, recommend, antimicrobial, penicillin, myonecrosi, treatment, is]	0.09090909090909091	2.6816169440340545	0.2437833585485504
prior	[is, hfref, patient, inhibitor, chronic, morbidity, use, reduce, prior, symptom, mortality, current, or, ace, beneficial]	0.06666666666666667	3.619886582626985	0.24132577217513232
prior	[prior, morbidity, mortality., inhibitor, contraindicat, ace, symptom, current, reduce, unles, hfref, or, recommend, are, patient]	0.06666666666666667	3.619886582626985	0.24132577217513232
treatment	[treatment, hfref, current, supplement, recommend, or, are, not, as, hf, patient, prior, symptom, nutritional]	0.07142857142857142	3.332204510175204	0.2380146078696574
blood	[diuretic, consider, diuresi, therapy, improve, may, be, infusion, addition, flow, bet, dopamine, low, loop, renal, functio, blood, renal, preserve, dose]	0.05	4.718498871295094	0.2359249435647547
dysfunction	[lv, is, severe, medical, or, dysfunction, morbidity, cad, reasonable, significant, hf, cardiovascular, therapy, cabg, patient, mortality, ef, improve]	0.05555555555555555	4.207673247529104	0.23375962486272797
clinical	[hf, symptomatic, reasonable, accord, hfpef, is, practice, clinical, publish, guideline, af, patient, management, improve]	0.07142857142857142	3.2521618025016674	0.23229727160726193
consider	[systemic, could, daily, celluliti, be, consider, prednisone, patient, nondiabetic, eg, mg, adult, corticosteroid, day]	0.07142857142857142	3.2521618025016674	0.23229727160726193
blood	[blood, inhibitor, patient, ace, reasonable, hypertension, hfpef, bloc, is, pressure, control, use, agent, arb, beta, patient]	0.0625	3.619886582626985	0.22624291141418656
cardiac	[hfref, beneficial, eg, management, or, stage, is, definitive, cardiac, whom, or, carefully, is, cardiac, anticipat, patient, plan, transplantation, recovery, mcs, select]	0.047619047619047616	4.718498871295094	0.22469042244262352
arni	[ii, arb, acei, bp, clas, or, nyha, then, arb, iii, adequate, sacubitril, discontinue, arb, or, arni, initiate, hf, acei, no, or]	0.047619047619047616	4.718498871295094	0.22469042244262352
consider	[clinically, consider, test, chronic, risk, available, patient, myocardial, stratification, or, such, may, fibrosi, additive, injury, hf, oth, as, be, measurement, biomarker]	0.047619047619047616	4.718498871295094	0.22469042244262352
behavioral	[gdmt, management, rehospitalization, implementation, hf, at, different, patient, hospital, reduce, barrier, risk, recommend, multidisciplinary, change, facilitate, risk, program, are, behavioral, disease, subsequent, hf, addres, high, readmission]	0.038461538461538464	5.817111159963204	0.2237350446139694
ciprofloxacin	[is, bas, doxycycline, ceftazidime, recommend, susceptibility, sr, vitro, imipenem, gentamicin, ciprofloxacin, or]	0.08333333333333333	2.6816169440340545	0.22346807866950452
condition	[or, agent, be, hf, oth, or, contribute, should, mellitu, condition, avoid, such, that, obesity, known, may, tobacco, control, diabete, cardiotoxic, as, lead, use]	0.043478260869565216	5.123963979403259	0.2227810425827504
cause	[culture, impetigo, aureu, staphylococcu, from, ecthyma, wheth, streptococcu, recommend, is, hemolytic, stain, cause, or, help, lesion, pus, exudate, are, skin, gram, or, identify]	0.043478260869565216	5.123963979403259	0.2227810425827504
polymerase	[lesion, peripheral, blood, wr, vzv, pcr, helpful, polymerase, disseminat, unexplain, be, reaction, hsv, might, establish, diagnosi, patient, skin, chain, infection]	0.05	4.430816798843313	0.22154083994216567
discontinuation	[discontinuation, rath, we, vap, hap, level, criteria, guide, plu, than, therapy, sug, criteria, clinical, use, alone, pct, clinical, patient, antibiotic]	0.05	4.430816798843313	0.22154083994216567
popliteal	[svs, aneurysm, examination, include, aortic, perform, aaa, assessment, or, suspect, physical, popliteal, abdominal, patient, an, known, femoral, arterie, recommend, that]	0.05	4.430816798843313	0.22154083994216567
restriction	[symptomatic, congestive, symptom, restriction, patient, is, sodium, reasonable, hf, reduce]	0.1	2.20619324731898	0.220619324731898
require	[antibiotic, patient, or, linezolid, hap, vancomycin, recommend, who, an, we, require, mrsa, rath, coverage, alternative, empiric, than]	0.058823529411764705	3.7376696182833684	0.2198629187225511
hap	[vap, inhal, hap, sug, is, sensitive, colistin, only, polymyxin, specie, adjunctive, patient, that, we, acinetobact, caus]	0.0625	3.5145260669691587	0.21965787918557242
implement	[mi, cardiovert, survival, ii, implement, post, implantable, caveat, clas, lvef, defibrillator, nyha, iii]	0.07692307692307693	2.8213788864092133	0.21702914510840104
dysfunction	[is, anatomy, coronary, viable, systolic, iib, ef, ischemic, survival, lv, severe, operable, myocardium, or, dysfunction, consider, patient, disease, be, improv, present, intent, heart, wheth, not, cabg, may]	0.037037037037037035	5.817111159963204	0.21544856148011865
bacteria	[cephalosporin, operation, agent, gram, gastrointestinal, recommend, axilla, or, metronidazole, combination, active, against, fluoroquinolone, bacteria, genital, female, as, are, perineum, such, tract, gi, negative, aft, anaerobe, tract, or, infection]	0.03571428571428571	5.817111159963204	0.20775396999868584
clinical	[recommend, fluid, than, therapy, clinical, lavage, initiate, plu, patient, bronchoalveolar, criteria, we, wheth, not, alone, vap, antibiotic, decide, use, or, criteria, balf, rath, suspect, clinical, hap, use, strem]	0.03571428571428571	5.817111159963204	0.20775396999868584
hap	[we, acinetobact, caus, not, use, vap, hap, sug, is, sensitive, colistin, only, specie, adjunctive, patient, rifampicin, that]	0.058823529411764705	3.5145260669691587	0.20673682746877403
hap	[adjunctive, is, vap, hap, sensitive, resistant, colistin, only, inhal, pathogen, that, polymyxin, sug, patient, we, carbapenem, caus]	0.058823529411764705	3.5145260669691587	0.20673682746877403
tid	[sr, day, penicillin, tid, qid, or, amoxicillin, mg, erysipeloid, treatment, is, mg, recommend]	0.07692307692307693	2.6816169440340545	0.20627822646415805
anthrax	[naturally, mg, treatment, sr, day, anthrax, is, oral, cutaneou, recommend, qid, penicillin, acquir]	0.07692307692307693	2.6816169440340545	0.20627822646415805
hydralazine	[gdmt, iv, hydralazine, is, isosorbide, clas, nyha, combination, african, american, hfref, dinitrate, iii, recommend]	0.07142857142857142	2.872672180796764	0.2051908700569117
scratch	[kg, follow, day, cat, is, kg, mg, patient, scratch, day, recommend, kg, mg, azithromycin, disease, day, kg, mg, additional, more, mg, day, patient]	0.043478260869565216	4.718498871295094	0.20515212483891712
therapy	[oth, reduce, unles, hfref, first, indication, already, patient, therapy, arb, especially, are, as, patient, morbidity, mortality, line, arb, alternatif, inhibitor, contraindicat, as, ace, reasonable, tak]	0.04	5.123963979403259	0.20495855917613034
vap	[all, bacilli, regimen, empiric, aureu, oth, vap, patient, negative, we, recommend, pseudomona, includ, s., gram, suspect, aeruginosa, coverage]	0.05555555555555555	3.619886582626985	0.2011048101459436
hiv	[or, present, hf, select, reasonable, hemochromatosi, hiv, screen, who, is, patient]	0.09090909090909091	2.20619324731898	0.20056302248354363
carefully	[carefully, is, patient, reasonable, selecteda, stage, prolong, durable, mcs, hfref, survival]	0.09090909090909091	2.20619324731898	0.20056302248354363
abscess	[or, antibiotic, mrsa, fail, initial, treatment, abscess, or, recommend, active, who, patient, defens, host, carbuncle, have, is, patient, an, impair, antibiotic, sir, hypotension, against, have, markedly]	0.07692307692307693	2.5982353350950036	0.19986425654576953
cardiac	[cause, hf, identify, or, present, might, patient, perform, noncardiac, examination, physical, history, disorder, development, thorough, that, behavior, accelerate, hf., or, progression, obtain, be, or, cardiac, should]	0.038461538461538464	5.123963979403259	0.19707553766935612
hap	[polymyxin, is, or, sensitive, colistin, only, polymyxin, specie, patient, that, intravenou, we, acinetobact, caus, polymyxin, vap, hap, recommend]	0.05555555555555555	3.5145260669691587	0.19525144816495324
prior	[are, intolerant, patient, arb, are, prior, morbidity, mortality, inhibitor, contraindicat, ace, symptom, current, who, reduce, unles, hfref, or, recommend]	0.05263157894736842	3.619886582626985	0.19052034645405183
left	[therapy, or, patient, cor, stage, investigational, palliative, care, additional, iia, device, or, iv, iii, cor, assist, studie, clas, are, transplant, nyha, left, or, cor, ventricular, consid, refractory]	0.037037037037037035	5.123963979403259	0.18977644368160215
hemodynamic	[reasonable, selecteda, acute, profound, nondurable, recovery, mcs, hfref, bridge, decision, use, includ, compromise, hemodynamic, bridge, percutaneou, or, carefully, is, patient, assist, extracorporeal, devex, as, ventricular]	0.04	4.718498871295094	0.18873995485180378
require	[control, allow, gdmt, nodal, if, meet, patient, be, rate, ventricular, lvef, or, near, patient, crt, ventricular, otherwise, require, atrioventricular, pharmacological, or, pac, criteria, useful, crt, can, will, ablation, pac, crt, af]	0.03225806451612903	5.817111159963204	0.18764874709558724
resistant	[sensitive, resistant, colistin, only, polymyxin, pathogen, that, polymyxin, or, patient, recommend, we, carbapenem, caus, intravenou, polymyxin, is, vap, hap]	0.05263157894736842	3.5145260669691587	0.1849750561562715
cardiac	[device, cardiac, transplantation, bridge, patient, therapy, refractory, mcs, inotropic, as, is, reasonable, gdmt, or, support, stage, are, who, eligible, continuou, intravenou, hf, await, therapy]	0.041666666666666664	4.430816798843313	0.1846173666184714
treatment	[are, empiric, proven, mssa, but, prefer, if, cefazolin, are, or, agent, above, is, vap, use, nafcillin, treatment, agent, one, not, necessary, oxacillin, treatment]	0.043478260869565216	4.207673247529104	0.18294231510996103
tigecycline	[against, specie, patient, recommend, we, acinetobact, caus, use, tigecycline, vap, hap]	0.09090909090909091	1.988469763474109	0.18076997849764628
hap	[hap, aeruginosa, aminoglycoside, patient, p., recommend, we, due, against, monotherapy, vap]	0.09090909090909091	1.988469763474109	0.18076997849764628
blood	[blood, should, material, culture, be, obtain, absces]	0.14285714285714285	1.252762968495368	0.17896613835648115
posaconazole	[mucor, infection, posaconazole, be, should, rhizopu, treat]	0.14285714285714285	1.252762968495368	0.17896613835648115
treatment	[mg, angiomatosi, qid, month, bid, week, or, mg, treatment, is, recommend, erythromycin, sr, doxycycline, bacillary]	0.06666666666666667	2.6816169440340545	0.17877446293560362
conjunction	[arni, chronic, morbidity, reduce, antagonist, clinical, mortality, system, conjunction, select, beta, recommend, patient, evidence, blocker, renin, angiotensin, is, bas, hfref, strategy, aldosterone, patient, inhibition]	0.041666666666666664	4.207673247529104	0.17531971864704599
despite	[hav, whom, is, despite, effect, or, adverse, judg, gdmt, patient, an, revascularization, ischemia, be, symptomatic, is, reasonable, coronary, cad, symptom, demonstrable, myocardial, hfpef, angina]	0.041666666666666664	4.207673247529104	0.17531971864704599
infection	[could, infection, see, nonpurulent, indicat, moderate, coverage, susceptible, s., systemic, include, clinician, are, celluliti, systemic, antibiotic, fig, many, sign, against, aureu, methicillin, mssa]	0.043478260869565216	4.02535169073515	0.17501529090152823
radionuclide	[echocardiography, resonance, inadequate, magnetic, can, or, useful, ventriculography, radionuclide, be, imag, when, volume, is, asses, lvef]	0.0625	2.772588722239781	0.17328679513998632
ambulatory	[ambulatory, mortality, patient, risk, subsequent, can, estimate, hf, useful, multivariable, validat, risk, be, or, score, hospitaliz]	0.0625	2.772588722239781	0.17328679513998632
cellular	[necrosi, antibodie, patient, manifestation, immediate, those, lymphoma, infection, as, defect, leukemia, familiar, transplant, certain, consultation, dermatologist, such, consid, organ, recipient, eg, or, receiv, anti-tumor, drug, cutaneou, or, those, lymphocytic, factor, immunosuppressive, cellular, monoclonal, immune]	0.029411764705882353	5.817111159963204	0.1710915047048001
resonance	[infiltrative, imag, when, burden, is, asses, resonance, magnetic, or, scar, reasonable, myocardial, process]	0.07692307692307693	2.20619324731898	0.16970717287069076
acceptable	[as, an, amphotericin, alternative, parapsilosi, isolat, candida, been, formulation, if, lipid, has, treat, acceptable, fluconazole]	0.06666666666666667	2.521274293958875	0.16808495293059167
treatment	[plague, or, mg, streptomycin, is, kg, doxycycline, mg, bid, recommend, sr, q12h, po, im, treatment, bubonic]	0.0625	2.6816169440340545	0.1676010590021284
channel	[calcium, are, channel, recommend, bloc, routine, treatment, not, as, patient, hfref, drug]	0.08333333333333333	1.988469763474109	0.16570581362284242
epidermoid	[culture, cyst, inflam, stain, pus, are, from, not, recommend, epidermoid, gram]	0.09090909090909091	1.8097779747307334	0.16452527043006668
novo	[de, detect, who, is, reasonable, kind, eligible, viability, any, cad, is, no, not, myocardial, present, known, noninvasive, imag, patient, revascularization, have, angina, patient, unles, novo, hf, ischemia]	0.037037037037037035	4.430816798843313	0.16410432588308568
therapy	[hf, diagnosi, can, influence, therapy, patient, endomyocardial, be, biopsy, that, is, when, present, suspect, useful, specific, would]	0.058823529411764705	2.772588722239781	0.1630934542493989
piperacillintazobact	[doripenem, such, or, cilastatin, hospitalization, cefepime, recommend, antipseudomonal, or, antibacterial, vancomycin, piperacillintazobact, as, carbapenem, empiric, imipenem, meropenem, are, antibiotic, therapy, plu, or]	0.045454545454545456	3.5145260669691587	0.1597511848622345
hydralazine	[ace, isosorbide, hypotension, can, or, renal, morbidity, prior, combination, insufficiency, current, given, or, contraindicat, can, an, who, mortality, be, symptomatic, or, hfref, dinitrate, arb, because, intolerance, be, reduce, or, useful, drug, unles, patient, hydralazine, inhibitor]	0.05714285714285714	2.772588722239781	0.15843364127084464
aortic	[valve, patient, replacement, aortic, mortality, aortic, surgical, is, iia, predict, stenosi, surgical, reasonable, critical]	0.07142857142857142	2.20619324731898	0.15758523195135568
prior	[current, because, or, ace, who, is, hfref, patient, or, angioedema, inhibitor, chronic, morbidity, are, use, reduce, arb, cough, prior, symptom, intolerant, recommend, mortality]	0.043478260869565216	3.619886582626985	0.157386373157695
antifungal	[should, or, antifungal, consider, empiric, be, antibiotic, antiviral]	0.125	1.252762968495368	0.156595371061921
carvedilol	[morbidity, mortality, blocker, ie, contraindicat, carvedilol, use, recommend, bisoprolol, mortality, reduce, unles, or, beta, is, patient, sustain, proven, prior, reduce, all, symptom, release, current, hfref, metoprolol, succinate]	0.037037037037037035	4.207673247529104	0.15583974990848531
hap	[sug, de-escalat, fix, be, patient, antibiotic, rath, we, vap, hap, that, than, therapy]	0.07692307692307693	1.988469763474109	0.15295921257493147
colistin	[antibiotic, polymyxin, or, systemic, due, vap, that, rath, both, sug, polymyxin, or, alone, negative, than, aminoglycoside, are, gram, bacilli, susceptible, inhal, antibiotic, patient, systemic, we, colistin, only]	0.037037037037037035	4.02535169073515	0.14908709965685737
asymptomatic	[channel, may, symptom, hf, asymptomatic, inotropic, negative, be, low, lvef, no, effect, mi, patient, nondihydropyridine, aft, blocker, harmful, calcium]	0.05263157894736842	2.8213788864092133	0.1484936256004849
clinical	[or, early, performance, provide, bas, reminder, gdmt, useful, recommend, response, postdischarge, identify, gdmt, asses, hf, improvement, appropriate, system, set, patient, evidence, hospital, care, clinician, is, advance, system, clinical, use, outpatient]	0.03333333333333333	4.430816798843313	0.1476938932947771
surgery	[functional, aft, repair, mitral, gdmt, only, selection, candidate, is, should, mitral, uncertain, insufficiency, valve, background, benefit, transcathet, mitral, or, surgery, consider, valve, careful, be]	0.041666666666666664	3.5145260669691587	0.14643858612371494
arni	[or, an, iii, tolerate, recommend, replacement, mortality, arni, an, ace, clas, ii, who, furth, nyha, symptomatic, is, hfref, patient, or, inhibitor, chronic, morbidity, reduce, arb]	0.04	3.619886582626985	0.1447954633050794
without	[is, cas, active, systemic, that, celluliti, without, receive, an, antimicrobial, sign, against, typical, infection, agent, streptococci, should]	0.058823529411764705	2.44981532997673	0.14410678411627822
hap	[bee, treat, against, we, recommend, empirically, antibiotic, aureu, activity, patient, hap, s., prescrib, an]	0.07142857142857142	1.988469763474109	0.14203355453386493
hemodynamic	[or, exacerbation, dur, chronic, experienc, it, symptomatic, gdmt, maintenance, absence, contraindication, hf, requir, gdmt, hospitalization, be, recommend, treatment, instability, hfref, continu, that, is, hemodynamic, patient]	0.04	3.5145260669691587	0.14058104267876634
trauma	[injection, mrsa, effective, or, against, sir, streptococci, drug, anoth, recommend, trauma, is, infection, penetrat, mrsa, associat, whose, is, use, elsewhere, both, colonization, mrsa, antimicrobial, or, nasal, celluliti, patient, evidence, vancomycin]	0.03333333333333333	4.207673247529104	0.1402557749176368
lipid	[formulation, lipid, be, should, rhizopu, treat, amphotericin, mucor, infection]	0.1111111111111111	1.252762968495368	0.1391958853883742
abscess	[recurrent, cultur, be, course, should, infection, abscess, early, drain]	0.1111111111111111	1.252762968495368	0.1391958853883742
infection	[skin, treat, should, tissue, infection, aspergillu, voriconazole, be, soft]	0.1111111111111111	1.252762968495368	0.1391958853883742
cardiac	[functional, useful, mortality, stable, cardiac, clinically, can, health, improve, hf, life, capacity, relat, be, hrqol, duration, rehabilitation, quality, exercise, patient]	0.05	2.772588722239781	0.13862943611198905
cardiac	[may, eligible, hf, support, who, continuou, control, despite, intravenou, device, transplantation, therapy, palliative, not, consider, optimal, mcs, select, long, symptom, term, as, cardiac, patient, gdmt, be, or, therapy, eith, stage, inotropic, are]	0.03125	4.430816798843313	0.13846302496385354
harmful	[intermittent, use, patient, or, parenteral, eith, absence, agent, oth, inotropic, reason, or, hf, than, harmful, positive, specific, care, continuou, intravenou, is, palliative, indication, potentially, long, term]	0.038461538461538464	3.5145260669691587	0.1351740794988138
etiology	[crt, gdmt, be, qrs, nyha, sinu, clas, consider, lvef, lbbb, who, duration, may, hf, rhythm, have, patient, ms, symptom, etiology, ischemic]	0.047619047619047616	2.8213788864092133	0.13435137554329588
sulbactam	[absence, definitive, broad, recommend, antimicrobial, ampicillin, or, vancomycin, piperacillin, sulbactam, carbapenem, treatment, plu, is, eith, etiologic, sr, diagnosi, tazobactam, spectrum]	0.05	2.6816169440340545	0.13408084720170274
conjunction	[clinical, patient, inhibitor, mortality, system, conjunction, select, beta, recommend, patient, arb, evidence, blocker, renin, angiotensin, is, bas, hfref, strategy, aldosterone, or, ace, inhibition, chronic, morbidity, reduce, antagonist]	0.037037037037037035	3.619886582626985	0.13406987343062907
ventricular	[undergo, pac, crt, anticipat, gdmt, be, are, replacement, lvef, placement, who, patient, ventricular, significant, device, or, new, have, useful, can, requirement]	0.047619047619047616	2.772588722239781	0.1320280343923705
achieve	[facilitate, patient, attention, hf, hospitalization, effective, design, system, care, ensure, gdmt, achieve, coordination, special, transition, that, deploy, be, care, is, should, prevent, that, care, effective, every, chronic]	0.037037037037037035	3.5145260669691587	0.13016763210996884
fatty	[fatty, nyha, reduce, use, cardiovascular, pufa, hfpef, is, adjunctive, hfref, supplementation, symptom, unles, or, hospitalization, reasonable, therapy, ii, mortality, as, contraindicat, omega, patient, clas, iv, polyunsaturat, acid]	0.037037037037037035	3.5145260669691587	0.13016763210996884
without	[lesion, pus, exudate, treatment, typical, skin, gram, or, culture, impetigo, reasonable, cas, from, ecthyma, without, is, stain]	0.058823529411764705	2.20619324731898	0.1297760733717047
clinical	[risk, reasonable, postdischarge, clinical, use, high, risk, is, biomarker, at, clinical, or, patient, tool, identify, event, prediction]	0.058823529411764705	2.20619324731898	0.1297760733717047
hydralazine	[recommend, mortality, as, hfref, selfdescrib, dinitrate, blocker, is, optimal, reduce, clas, unles, african, patient, iv, hydralazine, iii, inhibitor, beta, therapy, nyha, ace, isosorbide, american, receiv, morbidity, combination, contraindicat]	0.03571428571428571	3.619886582626985	0.12928166366524946
resuscitation	[benefit, oxygen, patient, not, is, resuscitation, hyperbaric, debridement, therapy, sr, may, not, because, been, delay, recommend, it, as, has, surgical, proven]	0.047619047619047616	2.6816169440340545	0.12769604495400258
persistent	[volume, active, overload, includ, risk, hf, term, persistent, state, consider, hav, have, vasopressin, cognitive, nonselective, may, be, or, hyponatremia, selective, wat, patient, are, concentration, improve, v2, vasopressin, at, eith, short, antagonist, or, hyponatremic, hospitaliz, maximization, symptom, who, gdmt, despite, hypervolemic, severe, serum, sodium, receptor, restriction, antagonist]	0.021739130434782608	5.817111159963204	0.12645893826006965
drainage	[be, drainage, perform, purulent, early, material, should]	0.14285714285714285	0.8826372268325126	0.12609103240464464
without	[low, perfusion, depres, output, pressure, potentially, evidence, use, patient, parenteral, significantly, agent, congestion, inotropic, hospitaliz, impair, blood, without, severe, or, dysfunction, harmful, document, without, or, is, cardiac, systolic]	0.03571428571428571	3.5145260669691587	0.12551878810604136
routine	[routine, not, endomyocardial, be, hf, biopsy, perform, patient, should, evaluation]	0.1	1.252762968495368	0.1252762968495368
initially	[all, initially, should, perform, lead, patient, present, be, electrocardiogram, hf]	0.1	1.252762968495368	0.1252762968495368
education	[care, education, patient, specific, hf, facilitate, should, hf, self, receive]	0.1	1.252762968495368	0.1252762968495368
without	[aureu, sug, icu, vap, mrsa, evidence, methicillinsensitive, an, risk, we, without, are, where, includ, s., aureu, suspect, mssa, who, factor, treat, treatment, s., against, agent, weak, active, patient, methicillin, quality, recommendation, very, resistance, low, isolate, bee, antimicrobial, are, not, resistant, empiric]	0.024390243902439025	5.123963979403259	0.12497473120495753
block	[addition, not, be, arb, bee, inhibitor, or, beta, aldosterone, ace, symptomatic, an, hfref, antagonist, an, already, may, indicat, consider, persistently, block, whom, tolerat, treat, are, an, who, is, patient]	0.034482758620689655	3.619886582626985	0.12482367526299948
without	[these, without, carbuncle, but, is, stain, studie, pus, are, from, typical, recommend, gram, reasonable, cas, treatment, abscess, culture]	0.05555555555555555	2.20619324731898	0.1225662915177211
persistent	[been, has, rivaroxaban, warfarin, potential, interaction, cost, basi, international, ratio, agent, be, warfarin, individualiz, characteristic, clinical, should, oth, patient, apixaban, if, an, normaliz, factor, permanent, selection, dabigatran, or, tak, therapeutic, preference, af, anticoagulant, tolerability, includ, patient, time, persistent, range, drug, paroxysmal, risk]	0.023809523809523808	5.123963979403259	0.12199914236674425
persistent	[tolerability, patient, risk, time, range, drug, tak, anticoagulant, be, been, includ, has, oth, rivaroxaban, potential, factor, permanent, interaction, cost, basi, clinical, international, ratio, agent, warfarin, individualiz, persistent, characteristic, paroxysmal, patient, apixaban, if, normaliz, af, an, selection, dabigatran, or, therapeutic, preference, warfarin, should]	0.023809523809523808	5.123963979403259	0.12199914236674425
discontinuation	[optimization, vasodilator, at, stable, diuretic, dose, aft, is, block, beta, patient, low, therapy, initiation, volume, block, beta, statu, therapy, successful, discontinuation, agent, inotropic, only, initiat, intravenou, be, recommend, should]	0.034482758620689655	3.5145260669691587	0.12119055403341926
clinical	[program, clinical, endors, quality, care, can, patient, hf, improv, nationally, beneficial, be, guideline, measure, quality, performance, bas, improvement, participation, practice, quality, registrie, bas]	0.043478260869565216	2.772588722239781	0.1205473357495557
harmful	[mg, m2, creatinine, ml, or, aldosterone, insufficiency, receptor, threaten, harmful, or, use, hyperkalemia, is, antagonist, meq, inappropriate, or, dl, rate, min, potassium, man, filtration, glomerular, life, mg, serum, because, is, woman, when, or, dl, estimat, renal, potentially]	0.02702702702702703	4.430816798843313	0.11975180537414361
prevalence	[s., suspect, patient, factor, treat, treatment, against, agent, active, patient, table, only, is, methicillin, mrsa, follow, any, known, resistance, prevalence, isolate, bee, antimicrobial, are, not, resistant, unit, where, empiric, aureu, sug, vap, mrsa, patient, an, risk, we, unit, where, includ]	0.025	4.718498871295094	0.11796247178237736
cardiac	[continuou, intravenou, maintain, significantly, hospitaliz, present, blood, severe, systemic, term, short, dysfunction, cardiac, patient, document, be, those, inotropic, preserve, systolic, end, reasonable, may, low, perfusion, depres, performance, output, support, pressure, organ, present, who]	0.030303030303030304	3.871201010907891	0.11730912154266337
hap	[recommend, not, hap, use, an, antipseudomonal, patient, aminoglycoside, we, are, bee, sole, treat, empirically, who, as, agent]	0.058823529411764705	1.988469763474109	0.11696880961612406
hap	[monotherapy, vap, hap, aeruginosa, quality, recommendation, very, patient, low, p., against, evidence, strong, we, due, recommend, aminoglycoside]	0.058823529411764705	1.988469763474109	0.11696880961612406
formal	[is, nyha, clas, sleep, or, hf, breath, patient, iv, sleep, sleepines, daytime, ii, reasonable, excessive, assessment, formal, disorder, suspicion]	0.05263157894736842	2.20619324731898	0.11611543406941999
critical	[are, reasonable, who, consideration, critical, valve, patient, replacement, deem, transcathet, careful, aortic, inoperable, is, aft, iia, stenosi, aortic, candidate]	0.05263157894736842	2.20619324731898	0.11611543406941999
blood	[not, or, blood, swab, aspirate, routinely, recommend, culture, biopsie, cutaneou, or, are]	0.16666666666666666	0.6931471805599453	0.11552453009332421
hap	[p., combination, antibiotic, shock, rath, which, who, test, remain, isolate, we, result, known, due, susceptible, than, is, are, or, monotherapy, high, sug, risk, death, vap, susceptibility, hap, when, antibiotic, septic, aeruginosa, therapy, use, at, patient]	0.02857142857142857	4.02535169073515	0.11501004830671856
incision	[incision, removal, perform, surgical, be, infection, should, plu, drainage, suture, site]	0.09090909090909091	1.252762968495368	0.11388754259048801
bacterial	[soft, skin, be, bacterial, day, tissue, should, duration, most, infection, treatment]	0.09090909090909091	1.252762968495368	0.11388754259048801
function	[should, when, include, monitor, indicat, function, renal, serial, electrolyte, serum, level]	0.09090909090909091	1.252762968495368	0.11388754259048801
diuretic	[patient, volume, relief, overload, be, symptom, use, hfpef, should, diuretic, due]	0.09090909090909091	1.252762968495368	0.11388754259048801
program	[persist, as, factor, predispos, be, program, should, so, continu, long, thi]	0.09090909090909091	1.252762968495368	0.11388754259048801
history	[inhibitor, administer, should, angiotensin, history, be, not, angioedema, neprilysin, receptor, patient]	0.09090909090909091	1.252762968495368	0.11388754259048801
therapy	[as, figure2, pharmacological, depict, gdmt, hfref, mainstay, therapy, should, figure, be]	0.09090909090909091	1.252762968495368	0.11388754259048801
dysfunction	[comorbiditie, implantation, severe, advanc, or, as, death, dysfunction, uncertain, survival, benefit, prolong, nonsudden, is, frailty, predict, hospitalization, meaningful, renal, or, high, risk, malignancy, icd, an, usefulnes, systemic, such, as, frequent, patient]	0.03225806451612903	3.5145260669691587	0.11337180861190835
quantitative	[section, occasionally, vap, rath, suspect, recogniz, antibiotic, below, will, is, clinician, culture, diagnose, quantitative, continu, sampl, result, diagnostic, whose, perform, threshold, noninvasive, than, some, that, are, howev, culture, quantitative, vap, patient, see, sug, that, we, be, panel, methodology, invasive, prefer, culture, vap, semiquantitative, be, withheld, invasive]	0.021739130434782608	5.123963979403259	0.1113905212913752
erythema	[count, mm3, drainage, wbc, may, cm, site, rate, induration, temperature, wound, as, incision, such, extend, min, indicat, heart, adjunctive, systemic, surgical, is, or, antimicrobial, beneficial, but, conjunction, associat, systemic, ºc, routinely, edge, response, not, be, infection, significant, erythema, therapy, from]	0.025	4.430816798843313	0.11077041997108283
anti-staphylococcal	[hospitalization, recent, nasal, is, or, prior, telavancin, mssa, colonization, mrsa, factor, are, or, anti-staphylococcal, antibiotic, vancomycin, mrsa, ceftaroline, daptomycin, an, or, where, infection, recent, first, cephalosporin, penicillin, linezolid, recommend, high, risk, generation]	0.03125	3.5145260669691587	0.10982893959278621
antagonist	[creatinine, ml, consider, appropriately, hf, dl, ef, admission, antagonist, or, meq, mg, within, patient, min, elevat, filtration, glomerular, receptor, might, hospitalization, bnp, estimat, select, hfpef, level, rate, aldosterone, potassium, decrease, year, be]	0.03125	3.5145260669691587	0.10982893959278621
reinforcement	[a., adjustment, self, supine, electrolyte, therapy, hf, patient, follow, as, contraindicat, hospital, palliative, establish, not, c., care, appropriate, barrier, discharge, transition, assessment, precipitant, limitation, visit, if, renal, condition, h., upright, or, volume, optimization, up, reinforcement, therapy, function, hf, adherence, follow, as, education, not, support, where, care, appropriate, comorbid, first, assessment, select, subsequent, hypotension, titration, postdischarge, hf, b., addres, previously, throughout, nee, before, hospice, care, caus, chronic, initiation, g., gdmt, be, management, hf, emergency, appropriate, postdischarge, hospitalization, assessment, should, optimal, statu, visit, consideration, at, plan, oral, care]	0.023255813953488372	4.718498871295094	0.10973253189058359
hap	[isolate, we, result, known, due, susceptible, than, recommend, is, are, antibiotic, or, monotherapy, high, risk, death, vap, susceptibility, hap, antibiotic, septic, aeruginosa, whom, therapy, not, use, at, an, patient, p., combination, shock, rath, which, who, test, are]	0.02702702702702703	4.02535169073515	0.10879328893878784
standard	[hfref, as, harmful, use, long, end, is, treatment, except, drug, medical, can, patient, stage, inotropic, potentially, standard, stabiliz, palliation, patient, term, be, positive, who, disease, infus]	0.038461538461538464	2.772588722239781	0.10663802777845313
left	[revascularization, percutaneou, intervention, especially, patient, bypas, hfpef, main, angina, is, left, coronary, disease, or, cabg, left, coronary, via, artery, or, hfref, anatomy, indicat, stenosi, equivalent, gdmt, graft, suitable, coronary, main, artery]	0.03225806451612903	3.2521618025016674	0.10490844524198926
resistant	[gram, we, not, resistance, isolate, bee, antimicrobial, patient, treatment, resistant, unit, local, icu, prescrib, rate, empiric, consider, an, risk, antimicrobial, patient, different, monotherapy, where, sug, suspect, are, available, table, class, only, an, from, antibiotic, follow, any, factor, negative, where, antipseudomonal, susceptibility, vap, are, patient, agent]	0.022222222222222223	4.718498871295094	0.10485553047322432
hap	[empirically, who, gram, activity, aeruginosa, hap, bacilli, p., oth, recommend, antibiotic, patient, prescrib, we, are, bee, negative, treat, against]	0.05263157894736842	1.988469763474109	0.10465630334074258
hap	[or, we, oth, recommend, antibiotic, combination, eith, vap, that, hap, linezolid, rath, vancomycin, antibiotic, or, treat, be, than, mrsa]	0.05263157894736842	1.988469763474109	0.10465630334074258
lipid	[lipid, should, low, hypertension, risk, contemporary, control, disorder, guideline, be, hf, accordance]	0.08333333333333333	1.252762968495368	0.10439691404128067
mupirocin	[mupirocin, nonbullou, eith, bid, treatment, day, or, bullou, impetigo, should, retapamulin, be]	0.08333333333333333	1.252762968495368	0.10439691404128067
blood	[white, tachypnea, such, min, as, or, aureu, beat, syndrome, cell, count, or, drainage, an, tachycardia, antibiotic, sir, made, response, should, administ, breath, against, s., temperature, absence, mm3, be, systemic, incision, decision, or, wbc, bas, min, inflammatory, presence, direct, adjunct, as, or, blood, cell]	0.023255813953488372	4.430816798843313	0.10304225113589101
hand	[joint, affect, capsule, hand, immunocompromis, injurie, or, have, day, disease, patient, have, preexist, especially, moderate, area, or, are, periosteum, is, have, edema, severe, or, therapy, sr, advanc, have, may, that, penetrat, antimicrobial, are, early, asplenic, injurie, preemptive, or, who, face, resultant, have, liv, recommend]	0.022727272727272728	4.430816798843313	0.10070038179189349
hap	[imipenem, cefepime, or, tazobactam, empiric, include, above, includ, hap, nafcillin, are, meropenem, or, mssa, treatment, agent, necessary, if, when, not, use, oxacillin, sug, we, are, one, mrsa, piperacillin, mssa, treatment, coverage, is, regiman, proven, that, not, but, empiric, prefer, indicat, cefazolin, coverage, is, levofloxacin]	0.022727272727272728	4.430816798843313	0.10070038179189349
left	[survival, stenosi, cad, graft, coronary, myocardium, artery, reasonable, anterior, iia, revascularization, intend, significant, stenosi, proximal, lad, patient, bypas, coronary, artery, present, revascularization, is, when, ef, region, improve, multivessel, coronary, viable, artery, diamet, systolic, lv, mild, moderate, is, descend, left, via, or, dysfunction]	0.023809523809523808	4.207673247529104	0.10018269636974056
disease	[useful, establish, measurement, or, is, bnp, hf, nt, prognosi, or, probnp, disease, severity, chronic]	0.14285714285714285	0.6931471805599453	0.09902102579427789
persistent	[should, patient, be, identify, foci, perform, studie, persistent, infection, undrain, imag, repeat, bacteremia]	0.07692307692307693	1.252762968495368	0.0963663821919514
blood	[aft, treatment, or, clearance, lesion, week, be, blood, stream, skin, resolution, should, infection]	0.07692307692307693	1.252762968495368	0.0963663821919514
bacterial	[sr, bacterial, skin, agent, fungal, differential, viral, infection, diagnosi, parasitic, should, lesion, include]	0.07692307692307693	1.252762968495368	0.0963663821919514
abscess	[neutrophil, if, patient, disorder, early, be, should, adult, childhood, evaluat, recurrent, abscess, began]	0.07692307692307693	1.252762968495368	0.0963663821919514
improve	[agent, erythropoietin, improve, should, patient, be, use, mortality, not, stimulat, hf, anemia, morbidity]	0.07692307692307693	1.252762968495368	0.0963663821919514
block	[rhythm, includ, heart, hf, maximum, who, rest, chronic, are, reduce, beneficial, at, patient, block, iii, gdem, receiv, tolerat, sinu, hospitalization, can, be, ivabradine, bpm, clas, ii, who, stable, beta, dose, nyha, symptomatic, are, lvef, at, hfref, rate]	0.02702702702702703	3.5145260669691587	0.09498719099916646
harmful	[is, life, dl, hyperkalemia, serum, potentially, or, antagonist, meq, mg, min, man, filtration, glomerular, or, because, receptor, woman, use, when, estimat, rate, aldosterone, potassium, harmful, or, m2, threaten, creatinine, ml, is, dl, renal, insufficiency, inappropriate, mg, or]	0.02702702702702703	3.5145260669691587	0.09498719099916646
withdrawn	[except, or, drug, are, possible, statu, patient, prior, drug, symptom, affect, calcium, potentially, eg, channel, or, withdrawn, bloc, amlodipine, adversely, drug, current, most, whenev, be, thiazolidinedione, nonsteroidal, clinical, should, hfref, or, drug, avoid, harmful, most, anti-inflammatory, antiarrhythmic, known]	0.02631578947368421	3.5145260669691587	0.09248752807813575
withdrawn	[drug, current, avoid, most, anti-inflammatory, hfref, antiarrhythmic, should, known, prior, drug, symptom, or, possible, statu, most, potentially, drug, affect, be, eg, except, or, withdrawn, drug, amlodipine, patient, adversely, calcium, clinical, are, whenev, channel, or, harmful, thiazolidinedione, nonsteroidal, bloc]	0.02631578947368421	3.5145260669691587	0.09248752807813575
blood	[hypertension, hfref, mm, systolic, gdmt, attain, blood, hg, titrat, should, pressure, patient, prescrib, be]	0.07142857142857142	1.252762968495368	0.08948306917824057
bubonic	[should, be, aspirat, from, diagnos, node, suppurative, lymph, gram, bubonic, stain, culture, plague, material]	0.07142857142857142	1.252762968495368	0.08948306917824057
exploration	[be, urgent, tissue, gangrene, suspect, surgical, exploration, involv, should, surgical, site, gas, perform, debridement]	0.07142857142857142	1.252762968495368	0.08948306917824057
standard	[patient, stage, term, treatment, harmful, positive, disease, infus, as, see, patient, use, long, page, end, is, hfref, recommendation, drug, potentially, medical, stage, inotropic, be, standard, can, except, who, stabiliz, start, palliation]	0.03225806451612903	2.772588722239781	0.08943834587870261
without	[absence, patient, anticoagulation, persistent, hf, paroxysmal, chronic, risk, reasonable, but, anticoagulation, is, without, have, stroke, contraindication, cardioembolic, who, an, factor, permanent, chronic, are, additional, af]	0.04	2.20619324731898	0.0882477298927592
without	[chronic, paroxysmal, without, af, hf, an, have, reasonable, contraindication, anticoagulation, chronic, patient, risk, stroke, cardioembolic, anticoagulation, additional, absence, who, is, but, factor, are, permanent, persistent]	0.04	2.20619324731898	0.0882477298927592
low	[piperacillin, quality, if, cefazolin, recommendation, or, treatment, very, regiman, agent, low, that, not, above, is, sug, indicat, vap, use, evidence, nafcillin, treatment, levofloxacin, one, imipenem, cefepime, tazobactam, are, not, include, coverage, empiric, includ, necessary, mrsa, oxacillin, mssa, we, meropenem, are, or, treatment, empiric, proven, agent, weak, when, mssa, but, is, prefer]	0.0196078431372549	4.430816798843313	0.08687876076163359
resistant	[suspect, confirm, recommend, when, or, doxycycline, methicillin, is, clindamycin, resistant, trimethoprim, or, staphylococcu, sulfamethoxazole, is, aureu]	0.125	0.6931471805599453	0.08664339756999316
hap	[respiratory, be, obtain, bee, rath, suspect, hap, accord, sample, result, perform, noninvasively, than, treat, non-vap, microbiologic, patient, studie, sug, empirically, that, we, treat]	0.043478260869565216	1.988469763474109	0.08645520710756996
left	[branch, duration, left, lvef, therapy, or, les, ii, iv, rhythm, ambulatory, ms, or, symptom, who, clas, resynchronization, iii, nyha, is, clas, have, great, lbbb, qrs, bundle, sinu, or, cardiac, indicat, gdmt, block, patient]	0.030303030303030304	2.8213788864092133	0.08549632989118829
asymptomatic	[survival, year, have, an, medical, expectation, prevent, is, appropriate, reasonable, lvef, placement, good, have, who, cardioverterdefibril, therapy, implantable, statu, reasonable, death, patient, are, functional, cardiomyopathy, day, sudden, ischemic, an, asymptomatic, are, icd, post-mi]	0.030303030303030304	2.8213788864092133	0.08549632989118829
blood	[hf, stage, blood, optimal, hg, should, pressure, increas, patient, be, risk, hypertension, at, mm, those]	0.06666666666666667	1.252762968495368	0.08351753123302454
blood	[or, evaluat, thi, be, resistant, microbe, since, or, biopsy, patient, obtain, surgical, may, aspiration, should, skin, be, aggressively, culture, they, lesion, caus, should, population, be, yeast, culture, blood, mold, excision]	0.06666666666666667	1.252762968495368	0.08351753123302454
clinical	[tissue, should, treat, antimicrobial, document, microbiologic, bas, clinical, infection, susceptibilitie, soft, isolat, organism, skin, be]	0.06666666666666667	1.252762968495368	0.08351753123302454
input	[disease, decid, use, oth, primary, should, specific, infectiou, consult, input, team, dermatology, agent, team, be]	0.06666666666666667	1.252762968495368	0.08351753123302454
post-mi	[is, clas, have, meaningful, receiv, recommend, than, scd, gdmt, least, patient, total, prevention, mortality, day, lvef, select, therapy, icd, post-mi, les, year, primary, more, reduce, expectation, or, symptom, who, while, at, nyha, survival, reasonable]	0.029411764705882353	2.8213788864092133	0.08298173195321215
clinical	[criteria, rath, suspect, hap, use, criteria, recommend, than, therapy, clinical, use, crp, initiate, plu, patient, we, clinical, wheth, not, alone, vap, antibiotic, decide, or]	0.041666666666666664	1.988469763474109	0.08285290681142121
clinical	[we, clinical, cpi, use, wheth, not, sug, alone, vap, antibiotic, decide, or, clinical, rath, suspect, hap, criteria, than, therapy, use, criteria, initiate, plu, patient]	0.041666666666666664	1.988469763474109	0.08285290681142121
penicillin	[treatment, document, penicillin, fasciiti, streptococcal, group, plu, is, recommend, necrotiz, clindamycin]	0.09090909090909091	0.9044562742271522	0.08222329765701385
left	[bas, hf, biomark, diastolic, prevent, be, cardiovascular, develop, new, ventricular, peptide, left, patient, or, natriuretic, can, onset, development, gdmt, at, useful, bas, specialist, care, team, optimiz, hf, risk, or, dysfunction, systolic, screen, includ, follow]	0.029411764705882353	2.772588722239781	0.08154672712469944
hemodynamic	[or, be, adequacy, impair, determin, who, therapy, or, patient, intracardiac, artery, cathet, exces, perform, from, be, whom, can, fil, should, pressure, monitor, invasive, clinical, distres, assessment, guide, evidence, hemodynamic, clinical, respiratory, pulmonary, perfusion, have]	0.029411764705882353	2.772588722239781	0.08154672712469944
cardiac	[severity, clinical, structural, therapy, that, useful, have, measurement, from, who, includ, change, significant, function, device, receiv, patient, be, repeat, or, have, measurement, remodel, information, treatment, who, might, significant, effect, had, have, event, hf, recover, or, statu, candidate, ef, cardiac, who, are, clinical, had, provide, have, who, may, or, experienc, gdmt]	0.02	4.02535169073515	0.08050703381470299
symptomatic	[hfref, be, patient, may, symptomatic, consider, persistently, an, arb, addition, gdmt]	0.09090909090909091	0.8826372268325126	0.08023974789386477
pct	[initiate, plu, use, patient, criteria, we, serum, wheth, not, alone, vap, antibiotic, clinical, decide, use, or, pct, rath, suspect, clinical, hap, recommend, than, criteria, therapy]	0.04	1.988469763474109	0.07953879053896437
ferritin	[be, transferrin, iron, ferritin, ng, statu, qol, might, ii, ml, ng, reasonable, hf, if, intravenou, ml, iii, deficiency, replacement, functional, is, saturation, iron, nyha, improve, clas, or, patient]	0.03571428571428571	2.20619324731898	0.07879261597567784
blood	[practice, clinical, be, publish, guideline, pressure, diastolic, hfpef, prevent, systolic, morbidity, control, should, accordance, blood, patient]	0.0625	1.252762968495368	0.0782976855309605
professionally	[hf, improv, goal, be, develop, guideline, measure, performance, bas, should, professionally, practice, quality, clinical, use, care]	0.0625	1.252762968495368	0.0782976855309605
diuretic	[significant, reduce, intravenou, fluid, treat, diuretic, be, should, overload, evidence, admit, morbidity, loop, hf, patient, promptly]	0.0625	1.252762968495368	0.0782976855309605
cardiomyopathy	[familial, obtain, be, dcm, dilat, generational, should, cardiomyopathy, dcm, diagnosi, patient, family, history, idiopathic, aid, establish]	0.0625	1.252762968495368	0.0782976855309605
etiology	[since, aerobic, plu, group, plu, or, be, community, piperacillin, linezolid, anaerobic, carbapenem, empiric, etiology, monomicrobial, plu, or, be, ceftriaxone, metronidazole, can, polymicrobial, tazobactam, or, mix, acquir, treatment, antibiotic, vancomycin, mrsa, broad, or, microbe, should, streptococcu, eg]	0.027777777777777776	2.772588722239781	0.07701635339554948
diuretic	[iia, intravenou, is, symptom, diuretic, addition, when, loop, inadequate, thiazide, b., eith, eg, second, diuretic, it, reasonable, intensify, use, high, a., dos, iia, relieve, is, diuretic, regiman, or, diuresi]	0.034482758620689655	2.20619324731898	0.07607562921789586
incision	[treatment, abscess, recommend, epidermoid, drainage, carbuncle, cyst, is, incision, inflam, large, furuncle]	0.08333333333333333	0.9044562742271522	0.07537135618559601
function	[perform, absence, should, lv, clinical, assessment, change, function, repeat, routine, not, measurement, treatment, or, intervention, be, statu]	0.058823529411764705	1.252762968495368	0.07369193932325695
cardiac	[mortality, day, sudden, select, symptom, icd, who, clas, post-mi, year, primary, iii, nyha, or, reduce, heart, expectation, is, have, disease, or, cardiac, survival, reasonable, gdmt, ischemic, patient, dcm, meaningful, lvef, recommend, therapy, nonischemic, death, chronic, scd, ii, total, prevention]	0.02564102564102564	2.8213788864092133	0.072343048369467
prevalence	[risk, at, hap, s., mrsa, prescrib, eith, who, an, risk, are, bee, not, within, factor, treat, ie, where, mortality, day, against, we, hospitalization, empirically, mrsa, unit, high, prior, are, antibiotic, or, sug, isolate, infection, resistant, is, known, aureu, have, activity, are, intravenou, prevalence, antibiotic, patient, mrsa, use, or, who, methicillin]	0.02	3.5145260669691587	0.07029052133938317
bacteria	[as, should, an, clavulanate, amoxicillin, aerobic, anaerobic, agent, or, bacteria, use, active, against, such, agent, both, be, antimicrobial]	0.05555555555555555	1.252762968495368	0.0695979426941871
nephritogenic	[help, from, antimicrobial, should, use, strain, eliminate, nephritogenic, be, systemic, infection, streptococcu, outbreak, post-streptococcal, community, pyogene, glomerulonephriti, dur]	0.05555555555555555	1.252762968495368	0.0695979426941871
persistent	[titrat, should, pressure, patient, prescrib, be, management, hypertension, overload, mm, aft, persistent, systolic, gdmt, volume, attain, blood, hg, hfpef]	0.05263157894736842	1.252762968495368	0.06593489307870358
implement	[early, microbiologic, step, obtain, material, or, sr, as, an, diagnostic, be, evaluation, histologic, alway, should, biopsy, lesion, implement, aspiration]	0.05263157894736842	1.252762968495368	0.06593489307870358
favorable	[receive, thromboembolism, admit, patient, favorable, an, venou, decompensat, benefit, hospital, anticoagulant, should, is, prophylaxi, medication, ratio, risk, if, hf]	0.05263157894736842	1.252762968495368	0.06593489307870358
vaccination	[prophylaxi, consultation, determine, if, recommend, official, be, postexposure, initiat, health, be, rabie, is, local, vaccination, should, sr, may, indicat]	0.05263157894736842	1.252762968495368	0.06593489307870358
acyclovir	[intravenou, acyclovir, disseminat, regiman, suspect, or, patient, should, hsv, be, sr, add, or, antimicrobial, cutaneou, infection, confirm, or, vzv]	0.05263157894736842	1.252762968495368	0.06593489307870358
dose	[should, ace, angiotensin, concomitantly, hour, inhibitor, be, within, or, inhibitor, not, dose, neprilysin, an, receptor, inhibitor, ace, administer, last]	0.05263157894736842	1.252762968495368	0.06593489307870358
remote	[prevent, use, all, be, or, recent, patient, should, cardiovascular, coronary, statin, or, mi, history, remote, event, symptomatic, acute, hf, syndrome]	0.05	1.252762968495368	0.0626381484247684
antifungal	[should, empiric, primary, antifungal, associat, infection, therapy, remain, yeast, mold, neutropenia, be, antibacterial, regiman, fev, sr, therefore, add, cause, table]	0.05	1.252762968495368	0.0626381484247684
period	[extend, therapy, is, be, should, not, duration, if, antimicrobial, but, infection, thi, improv, has, time, day, recommend, treatment, period, within]	0.05	1.252762968495368	0.0626381484247684
wound	[those, preemptive, exception, face, is, irrigation, which, cautiou, be, debridement, recommend, wound, closure, manag, antibiotic, copiou, should, primary, wound, not]	0.05	1.252762968495368	0.0626381484247684
pilonidal	[prompt, material, hidradeniti, search, at, caus, suppurativa, foreign, absces, previou, such, as, local, or, site, cyst, recurrent, pilonidal, should, infection]	0.05	1.252762968495368	0.0626381484247684
diuretic	[loop, patient, daily, are, or, if, receiv, dose, chronic, intravenou, equal, diuretic, dose, oral, exce, should, their, already, therapy, initial]	0.05	1.252762968495368	0.0626381484247684
daptomycin	[be, already, add, not, administer, should, empiric, linezolid, agent, or, bee, or, positive, administration, oth, ceftaroline, daptomycin, gram, vancomycin, activity, if]	0.047619047619047616	1.252762968495368	0.05965537945216038
without	[one, antibiotic, factor, negative, where, aeruginosa, vap, are, agent, gram, we, p., resistance, without, are, isolate, bee, treatment, resistant, icu, prescrib, empiric, who, consider, risk, bee, antimicrobial, patient, monotherapy, treat, against, sug, suspect, active]	0.029411764705882353	1.988469763474109	0.05848440480806203
posaconazole	[be, fusarium, treat, dose, infection, voriconazole, iv, high, posaconazole, specie, or, should]	0.08333333333333333	0.6931471805599453	0.057762265046662105
remote	[or, evidence, recent, patient, should, coronary, reduc, bas, blocker, mi, history, ef, remote, acute, reduce, syndrome, or, use, beta, all, mortality, be]	0.045454545454545456	1.252762968495368	0.05694377129524401
lipid	[or, isolat, candida, sr, been, formulation, if, lipid, be, specie, has, skin, treat, should, soft, infection, an, candida, amphotericin, echinocandin, tissue, parapsilosi]	0.045454545454545456	1.252762968495368	0.05694377129524401
blood	[antimicrobial, who, as, sign, slough, cell, hypotension, severely, heart, or, patient, clinical, per, those, evidence, such, organ, minute, consider, have, bulla, immunocompromis, or, white, as, sign, tachypnea, cell, compromis, abnormal, respiratory, or, patient, fail, those, skin, coverage, minute, beat, may, broad, treatment, or, infection, spectrum, rate, count, deep, or, those, who, are, tachycardia, blood, oral, dysfunction, be, or, breath, systemic, infection, per, antibiotic, such, rate, temperature]	0.015151515151515152	3.7376696182833684	0.05663135785277831
microscopic	[severe, biopsie, chemotherapy, cutaneou, malignancy, culture, or, injurie, be, examination, patient, swab, immunodeficiency, aspirate, should, immersion, neutropenia, mediat, cell, bite, microscopic, animal, consider]	0.043478260869565216	1.252762968495368	0.05446795515197252
mineralocorticoid	[closely, perform, potassium, antagonist, man, clas, filtration, function, glomerular, have, ii, careful, patient, should, woman, are, initiation, nyha, be, who, dl, lvef, estimat, renal, or, level, rate, receptor, potassium, antagonist, morbidity, be, elevat, clas, have, ii, mg, iv, monitor, contraindicat, should, m2, nyha, dos, creatinine, ml, risk, dl, renal, follow, at, or, level, receptor, recommend, should, diuretic, antagonist, mortality, thereaft, be, peptide, insufficiency, unles, mg, mineralocorticoid, or, level, aldosterone, history, natriuretic, cardiovascular, hyperkalemia, patient, plasma, receptor, should, be, prior, meq, reduce, consider, hospitalization, minimize, or, level, aldosterone, min]	0.011363636363636364	4.718498871295094	0.05361930535562607
without	[is, tetanu, toxoid, prefer, has, vaccination, td, sr, within, be, year, toxoid, if, tdap, should, given, without, form, patient, ove, not, administer, been, previously]	0.041666666666666664	1.252762968495368	0.05219845702064033
cardiac	[appropriate, be, cardiac, treat, biomarker, troponin, as, acute, test, serum, should, optimally, acs, prognosi, promptly, ecg, condition, patient, precipitat, decompensation, identifi, includ, overall, hf]	0.041666666666666664	1.252762968495368	0.05219845702064033
colonization	[pathogen, fissur, eradicate, scal, celluliti, recurrent, toe, space, incidence, because, treat, examine, extremity, should, or, reduce, clinician, interdigital, low, infection, may, carefully, colonization, maceration]	0.041666666666666664	1.252762968495368	0.05219845702064033
cardiac	[cardiac, guideline, history, pressure, clinical, control, symptomatic, acs, accordance, hf, prevent, structural, blood, includ, absence, be, lv, hypertrophy, hypertension, abnormalitie, patient, should, practice, or, mi]	0.04	1.252762968495368	0.05011051873981472
trauma	[negative, vancomycin, aft, or, open, is, sr, recommend, bacilli, agent, gram, empiric, therapy, initial, should, infection, trauma, active, add, against, immunocompromis, muscle, an, enteric, patient, be]	0.038461538461538464	1.252762968495368	0.0481831910959757
day	[should, alone, when, is, yield, active, be, agent, an, oral, against, s., aureu, agent, streptococci, oral, culture, recommend, unles, therapy, day, or, ecthyma, impetigo, regiman, penicillin]	0.038461538461538464	1.252762968495368	0.0481831910959757
area	[recommend, are, area, treatment, underlie, or, cutaneou, predispos, disorder, factor, such, affect, elevation, as, edema]	0.06666666666666667	0.6931471805599453	0.046209812037329684
crt	[pattern, not, ii, patient, ms, symptom, crt, recommend, non-lbbb, qrs, nyha, clas, is, or, duration]	0.06666666666666667	0.6931471805599453	0.046209812037329684
amphotericin	[posaconazole, voriconazole, echinocandin, soft, skin, treat, amphotericin, tissue, infection, alternatively, or, formulation, week, aspergillu, lipid]	0.06666666666666667	0.6931471805599453	0.046209812037329684
block	[cor, as, or, iv, beta, gdmt, acei, and, clas, diuretic, nyha, hfref, block, arb, stage, need]	0.0625	0.6931471805599453	0.04332169878499658
infection	[or, infection, vancomycin, imipenem, severe, tazobactam, eith, recommend, plu, regiman, meropenem, as, is, piperacillin, empiric, reasonable]	0.0625	0.6931471805599453	0.04332169878499658
transplantation	[until, cardiogenic, mcs, systemic, inotropic, coronary, should, or, support, preserve, problem, resolution, precipitat, perfusion, intravenou, performance, temporary, shock, heart, therapy, revascularization, receive, acute, maintain, endorgan, eg, transplantation, patient, definitive]	0.034482758620689655	1.252762968495368	0.043198723051564414
persistent	[support, remain, is, circulatory, hemodynamic, who, empiric, systolic, whose, require, fluid, associat, or, pulmonary, may, carefully, therapie, perfusion, statu, have, mechanical, resistance, persistent, standard, initial, nee, whose, hf, is, or, despite, vasoactive, symptom, systemic, acute, who, transplantation, therapy, or, patient, consideration, useful, renal, whose, worsen, be, adjustment, is, or, despite, agent, can, function, pressure, parenteral, symptom, mcs, monitor, invasive, who, uncertain, therapy, or, vascular, low, select]	0.015151515151515152	2.772588722239781	0.04200892003393608
erythema	[cutaneou, radiation, among, transplant, differential, infection, diagnosi, reaction, erythema, vasculiti, recipient, should, lesion, eruption, chemotherapy, drug, graftversu, malignancy, syndrome, underlie, leukocytoclastic, include, sr, infiltration, skin, allogeneic, disease, addition, host, multiforme, sweet, induc, or]	0.030303030303030304	1.252762968495368	0.03796251419682933
persistent	[or, stroke, ischemic, should, history, age, receive, patient, an, factor, permanent, or, stroke, chronic, year, contraindication, cardioembolic, af, anticoagulant, diabete, persistent, therapy, transient, paroxysmal, chronic, risk, additional, attack, absence, previou, anticoagulation, hf, hypertension, mellitu]	0.029411764705882353	1.252762968495368	0.036845969661628473
persistent	[attack, diabete, previou, factor, permanent, stroke, hypertension, cardioembolic, additional, history, absence, or, ischemic, persistent, chronic, age, receive, paroxysmal, mellitu, patient, af, an, or, year, should, chronic, risk, hf, transient, stroke, contraindication, anticoagulation, anticoagulant, therapy]	0.029411764705882353	1.252762968495368	0.036845969661628473
size	[hf, contribute, or, alternative, symptom, acute, those, size, pulmonary, cause, asses, patient, diseas, cardiac, heart, suspect, x-ray, or, new, decompensat, pulmonary, may, should, patient, undergo, detect, hf, that, or, present, congestion, oth, onset, che]	0.029411764705882353	1.252762968495368	0.036845969661628473
glucose	[function, count, blood, glucose, electrolyte, nitrogen, serum, evaluation, urinalysi, hormone, patient, present, stimulat, test, urea, includ, hf, calcium, liv, cell, fast, lipid, measurement, initial, should, profile, magnesium, complete, laboratory, blood, creatinine, include, thyroid, serum]	0.029411764705882353	1.252762968495368	0.036845969661628473
benzathine	[predispos, be, year, such, should, oral, patient, despite, antibiotic, penicillin, or, benzathine, episode, week, prophylactic, erythromycin, per, penicillin, administration, every, control, who, bid, or, week, as, factor, consider, have, attempt, treat, celluliti, intramuscular, or]	0.029411764705882353	1.252762968495368	0.036845969661628473
ventricular	[hfref, or, indication, consider, be, ventricular, may, aneurysmectomy, includ, arrhythmia, carefully, intractable, lv, remodel, select, specific, patient, reverse, hf, surgical]	0.05	0.6931471805599453	0.03465735902799726
remote	[blocker, inhibitor, mi, contraindicat, convert, or, history, ef, angiotensin, intolerant, remote, are, unles, ace, acute, reduce, syndrome, or, enzyme, use, receptor, patient, symptomatic, ace, all, mortality, be, hf, prevent, inhibitor, recent, patient, appropriate, should, angiotensin, coronary, reduc]	0.02702702702702703	1.252762968495368	0.03385845860798292
syndrome	[are, patient, unles, ace, acute, reduce, syndrome, enzyme, inhibitor, use, receptor, patient, symptomatic, all, angiotensin, mortality, be, hf, prevent, inhibitor, or, recent, appropriate, should, angiotensin, coronary, reduc, blocker, ace, mi, contraindicat, convert, or, history, ef, intolerant, remote]	0.02702702702702703	1.252762968495368	0.03385845860798292
diuretic	[consider, an, nitroprusside, may, be, or, nesiritide, decompensat, absent, adjuvant, hypotension, intravenou, is, diuretic, dyspnea, relief, symptomatic, if, hf, therapy, as, nitroglycerin, acute, admit, patient]	0.04	0.6931471805599453	0.027725887222397813